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Enes Dasdemir Logo
Welcome to my world

I'mEnes Dasdemir

Computational Biologist Spatial Multi-Omics Researcher Data Scientist
Exploring the spatial universe of cells from Istanbul to Houston

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My Journey

Education & Career

From the historic shores of Istanbul to the cutting-edge research facilities of Houston, each step shaped my path in computational biology.

Follow the route: Istanbul · Thessaloniki · Houston

Undergraduate Studies

Istanbul University

Istanbul, Türkiye
2016 - 2021

Five years in the Biology program on the shores of the Bosphorus. This was a wet lab education built on the core molecular biology techniques and bench work, long before any computation entered the picture.

Molecular BiologyWet Lab TechniquesBench Research

Beyond the Lab

Faculty Basketball Team

Featured Landmark: Maiden's Tower

An exchange year abroad, sailing west across the Aegean.

Erasmus Exchange

Aristotle University of Thessaloniki

Thessaloniki, Greece
Erasmus Programme

A semester under the White Tower, trading the Bosphorus for the Thermaic Gulf, and learning how much of science is built between cultures.

European Research ExchangeCross-cultural Collaboration

Beyond the Lab

Erasmus Basketball
Music Ensemble
Theater Team

Featured Landmark: White Tower of Thessaloniki

Home again, where two continents meet.

Undergraduate Research Fellow

Koç University

Istanbul, Türkiye
2021

Back in Istanbul, finishing my degree and joining a summer research fellowship on biomolecular systems through the lens of quantum biology, under Dr. Özgür Müstecaplıoğlu. We studied how quantum information phenomena play out inside living systems, and it grew my footing in both physics and computation. The coding that followed, I taught myself.

Quantum BiologyQuantum InformationScientific Computing

Featured Landmark: Taksim Tünel

A flight west, bound for Texas.

Ph.D. in Biochemistry

University of Houston · Gunaratne Lab

Houston, Texas
2022 - 2026

Doctoral research in genomics and computational biology in the Gunaratne Lab, building the sequencing, single cell, and spatial pipelines that turn raw reads into biology. Alongside the PhD, I worked as a bioinformatician for the university's Seq N Edit Core.

BioinformaticsSingle cell & Spatial GenomicsNGS PipelinesCore Facility

Featured Landmark: Turkish Airlines · The Crossing

Deeper into the Texas Medical Center.

Graduate Researcher

MD Anderson Cancer Center · Abbas Lab

Houston, Texas
2023 - 2026

Mapping the leukemia microenvironment with spatial multi-omics in the Abbas Lab, bridging computation and the clinic to understand how acute myeloid leukemia survives and resists therapy.

AML & LeukemiaSpatial Multi-omicsTumor Microenvironment

Featured Landmark: Texas Medical Center

Research & Publications

My Work

Peer-reviewed and in-progress work in spatial multi-omics, computational biology, and the leukemia microenvironment.

7 papers4 peer-reviewed3 in progress
iScience (Cell Press)
iScience (Cell Press)2025
Featured

Integrative spatial multi-omics reveal niche-specific inflammatory signaling and differentiation hierarchies in AML

My flagship study, resolving how the acute myeloid leukemia niche shapes inflammatory signaling and differentiation hierarchies through integrative spatial multi-omics.

Spatial Multi-omicsAMLCell Press
Nature Communications
Nature Communications2024

Comprehensive characterization of IFNγ signaling in acute myeloid leukemia reveals prognostic and therapeutic strategies

Dissecting interferon-γ signaling across AML to surface prognostic markers and actionable therapeutic strategies.

IFNγ SignalingAMLImmuno-oncology
npj Precision Oncology
npj Precision Oncology2025

Multimodal spatial proteomic profiling in acute myeloid leukemia

High-plex spatial proteomics resolving the cellular architecture of the AML bone-marrow microenvironment.

Spatial ProteomicsAMLBone Marrow
Leukemia & Lymphoma
Leukemia & Lymphoma2025

Mutation dynamics from diagnosis to relapse in acute myeloid leukemia with chromosomal 7 deletions

Tracking clonal mutation dynamics from diagnosis to relapse in del(7) acute myeloid leukemia.

Clonal EvolutionAMLdel(7)
bioRxiv
bioRxiv2025Under Revision

Macrophage-secreted pyrimidine metabolites confer chemotherapy resistance in acute myeloid leukemia

How macrophage-derived pyrimidine metabolites drive chemotherapy resistance in AML.

ChemoresistanceMetabolismMicroenvironment
Nature ImmunologyIn Revision

DYRK1A controls CD47 endocytic degradation and cancer immune surveillance

Identifying DYRK1A as a regulator of CD47 turnover and the “don’t-eat-me” axis in cancer immune surveillance.

CD47Immune SurveillanceDYRK1A
Cell Reports MedicineIn Submission

CALM: A Comprehensive Atlas of Leukemia and its Microenvironment

Building CALM, a comprehensive single-cell and spatial atlas of leukemia and its microenvironment.

AtlasLeukemiaSingle-cell
Get In Touch

Let's Collaborate

Interested in spatial multi-omics, bone marrow research, or computational biology? I'm always open to discussing new ideas, collaborations, or opportunities.

Send a Message
Global Horizon
Istanbul
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LAT 41.0082°N
LNG 28.9784°E
Houston
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LAT 29.7604°N
LNG 95.3698°W

© Enes Dasdemir, PhD

SPATIAL MULTI-OMICS • COMPUTATIONAL BIOLOGY • DATA SCIENCE